B.Pharm. Bachelor of Pharmacy Pharmacology

Question 1

Which receptor type mediates the bronchodilatory effect of epinephrine in the lungs?

Accepted Answer

Beta-2 adrenergic

Answer

Alpha-1 adrenergic

Answer

Muscarinic M2

Answer

Dopamine D2

Question 2

What is the primary mechanism of action of aspirin (acetylsalicylic acid)?

Accepted Answer

Irreversible inhibition of COX-1 and COX-2

Answer

Reversible inhibition of COX-1 and COX-2

Answer

Selective COX-2 inhibition

Answer

Inhibition of lipoxygenase

Question 3

Which pharmacokinetic parameter describes the fraction of an administered drug that reaches systemic circulation unchanged?

Accepted Answer

Bioavailability

Answer

Volume of distribution

Answer

Clearance

Answer

Half-life

Question 4

The therapeutic index of a drug is calculated as:

Accepted Answer

LD50 / ED50

Answer

ED50 / LD50

Answer

EC50 / LD50

Answer

LD50 / EC50

Question 5

Which class of antihypertensive drugs acts by blocking angiotensin-converting enzyme (ACE)?

Accepted Answer

ACE inhibitors

Answer

ARBs

Answer

Beta-blockers

Answer

Calcium channel blockers

Question 6

First-pass metabolism primarily occurs in which organ after oral drug administration?

Accepted Answer

Liver

Answer

Kidney

Answer

Lung

Answer

Small intestine only