Compounding Flashcards
7 cards from real PTCE practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 Compounding flashcards as text
The term 'tonicity' in compounded ophthalmic solutions refers to:
Answer: Osmotic pressure relative to blood or tears
Tonicity describes the osmotic pressure of a solution compared to body fluids; ophthalmic preparations should be isotonic (~0.9% NaCl equivalent).
Which of the following is an example of a compounded preparation that requires protection from light during storage?
Answer: Nitroglycerin transdermal gel
Nitroglycerin is photosensitive and must be stored in amber containers to prevent degradation.
When calculating the amount of active drug needed for a compounded preparation, a technician uses the formula: quantity = (strength desired × volume desired) / stock strength. This is an application of which concept?
Answer: Dilution equation (C1V1 = C2V2)
C1V1 = C2V2 is the dilution equation used to calculate how much stock solution is needed to prepare a desired concentration and volume.
A pharmacy must comply with USP when handling which category of compounding ingredients?
Answer: Hazardous drugs (HDs)
USP specifically governs safe handling, storage, and compounding of hazardous drugs to protect personnel and the environment.
Which equipment is used to measure small volumes of liquid (< 1 mL) accurately in a compounding pharmacy?
Answer: Calibrated oral syringe or micropipette
Calibrated oral syringes and micropipettes provide the accuracy needed for measuring very small liquid volumes.
What does 'geometric dilution' ensure when incorporating a small amount of a potent drug powder into a larger base?
Answer: Uniform distribution of the drug throughout the preparation
Geometric dilution progressively doubles the mixture to ensure the potent drug is evenly distributed before full incorporation.
A technician is compounding a preparation requiring a pH of 4.5. Which ingredient would be MOST appropriate as a buffer?
Answer: Sodium acetate / acetic acid buffer system
An acetate buffer (acetic acid + sodium acetate) provides effective buffering capacity in the pH range of approximately 3.6–5.6.