PTCB Pharmacology #1 2

Question 1

Which drug class do "-pril" suffix drugs belong to?

Accepted Answer

ACE inhibitors

Answer

ARBs

Answer

Beta-blockers

Answer

Calcium channel blockers

Question 2

What is the primary mechanism of proton pump inhibitors (PPIs)?

Accepted Answer

Irreversibly inhibit H+/K+ ATPase enzyme in parietal cells

Answer

Neutralize stomach acid

Answer

Block histamine H2 receptors

Answer

Coat stomach mucosa

Question 3

Thiazide diuretics like hydrochlorothiazide work primarily by:

Accepted Answer

Inhibiting sodium reabsorption in the distal convoluted tubule

Answer

Inhibiting carbonic anhydrase in the proximal tubule

Answer

Blocking aldosterone receptors in the collecting duct

Answer

Blocking sodium-potassium-chloride cotransporter in the loop of Henle

Question 4

Benzodiazepines exert their sedative effects by:

Accepted Answer

Enhancing GABA-A receptor activity by increasing chloride channel opening frequency

Answer

Blocking NMDA glutamate receptors

Answer

Inhibiting serotonin reuptake

Answer

Activating mu-opioid receptors

Question 5

Which of the following correctly describes pharmacokinetics?

Accepted Answer

What the body does to the drug: absorption, distribution, metabolism, excretion

Answer

The study of drug mechanisms on the body

Answer

The study of drug-receptor interactions

Answer

The measure of drug toxicity at the cellular level

Question 6

Which receptor do beta-blockers primarily block to reduce heart rate?

Accepted Answer

Beta-1 adrenergic receptors

Answer

Alpha-1 adrenergic receptors

Answer

Muscarinic (M2) receptors

Answer

Beta-2 adrenergic receptors