Practice Test GeeksPANRE Test Practice Test
← All PANRE Flashcard Decks

Endocrinology Flashcards

7 cards from real PANRE practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

Read the first 7 Endocrinology flashcards as text

  1. A 55-year-old woman with type 2 diabetes has an eGFR of 38 mL/min/1.73m². Which medication should be discontinued?

    Answer: Metformin

    Metformin is contraindicated when eGFR falls below 30 and should be used with caution (many guidelines recommend discontinuing) at eGFR <45 due to risk of lactic acidosis.

  2. Which finding is most consistent with primary hyperaldosteronism (Conn syndrome)?

    Answer: Hypokalemia with hypertension

    Primary hyperaldosteronism causes sodium retention and potassium wasting, resulting in hypokalemia and hypertension.

  3. A patient with suspected pheochromocytoma should be screened using which initial test?

    Answer: 24-hour urine catecholamines and metanephrines

    24-hour urine catecholamines and fractionated metanephrines (or plasma metanephrines) are the recommended biochemical screening tests for pheochromocytoma.

  4. A 40-year-old man has central obesity, moon facies, and purple striae. His 24-hour urine free cortisol is elevated. What is the next best step?

    Answer: Low-dose dexamethasone suppression test

    After confirming hypercortisolism with elevated urine free cortisol, a low-dose dexamethasone suppression test helps confirm the diagnosis of Cushing syndrome before localization.

  5. Which thyroid cancer subtype has the worst prognosis?

    Answer: Anaplastic

    Anaplastic (undifferentiated) thyroid carcinoma is extremely aggressive with median survival of only 3-5 months after diagnosis.

  6. A patient with MEN2A would most likely have which combination of conditions?

    Answer: Medullary thyroid cancer, pheochromocytoma, and hyperparathyroidism

    MEN2A (Multiple Endocrine Neoplasia type 2A) is characterized by medullary thyroid carcinoma, pheochromocytoma, and primary hyperparathyroidism.

  7. Which insulin regimen best mimics physiologic insulin secretion in type 1 diabetes?

    Answer: Basal-bolus regimen with glargine plus rapid-acting insulin

    A basal-bolus regimen using long-acting insulin (e.g., glargine) for basal needs and rapid-acting insulin at meals best approximates normal pancreatic insulin secretion.