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Dermatology Flashcards

7 cards from real PANRE practice questions. Tap to flip, then mark Knew It or Still Learning โ€” missed cards come back until you master them.

Read the first 7 Dermatology flashcards as text
  1. A 40-year-old presents with pruritic, excoriated papules on the interdigital web spaces, wrists, and genitalia. His wife has similar symptoms. Mineral oil preparation of a skin scraping reveals what finding?

    Answer: Mites, eggs, or feces (scybala)

    Scabies is confirmed by identifying Sarcoptes scabiei mites, eggs, or scybala (fecal pellets) on microscopy of skin scrapings from burrows.

  2. A 65-year-old man presents with a non-healing, indurated ulcer on his lower lip with raised, everted edges. He has a 40 pack-year smoking history and dentures. Biopsy shows invasive squamous cell carcinoma. What is the most important prognostic factor?

    Answer: Regional lymph node involvement

    Regional lymph node metastasis is the single most important prognostic factor for cutaneous and lip squamous cell carcinoma, significantly worsening 5-year survival.

  3. Which statement about seborrheic keratoses is correct?

    Answer: They are benign and have a 'stuck-on' appearance

    Seborrheic keratoses are benign epidermal proliferations with a characteristic 'stuck-on' waxy appearance and horn pseudocysts; they require no treatment unless symptomatic.

  4. A 32-year-old woman on isotretinoin for severe acne asks about contraception. What is the required minimum contraception strategy according to iPLEDGE?

    Answer: Two forms of contraception simultaneously or abstinence

    iPLEDGE mandates two simultaneous forms of effective contraception (or confirmed abstinence) due to isotretinoin's severe teratogenicity (Pregnancy Category X).

  5. A 55-year-old presents with thick, silvery-white scales overlying well-demarcated erythematous plaques on the elbows and knees. Removing a scale produces punctate bleeding (Auspitz sign). What systemic comorbidity should be screened for?

    Answer: Psoriatic arthritis

    Psoriatic arthritis occurs in up to 30% of patients with psoriasis and should be routinely screened for, as early detection prevents joint destruction.

  6. A 25-year-old male has a 2 cm pink, dome-shaped nodule on his back that was removed and found to contain a cyst wall lined by stratified squamous epithelium with a granular layer, filled with cheesy keratin. What is the correct diagnosis?

    Answer: Epidermoid cyst

    Epidermoid cysts (formerly 'sebaceous cysts') are lined by stratified squamous epithelium with a granular layer and contain laminated keratin; pilar cysts lack the granular layer.

  7. A 70-year-old woman presents with large, tense bullae on the flexural surfaces. Direct immunofluorescence shows linear IgG and C3 deposits at the dermal-epidermal junction. What is the diagnosis?

    Answer: Bullous pemphigoid

    Bullous pemphigoid is characterized by tense bullae (subepidermal blistering) with linear IgG and C3 deposits at the BMZ on DIF, targeting BP180 and BP230 antigens.