MTM Respiratory Disease Management 3

Question 1

A patient prescribed an inhaled corticosteroid (ICS) for asthma asks how to prevent oral candidiasis. What is the MOST effective counseling point?

Accepted Answer

Rinse the mouth and gargle with water after each use

Answer

Take the inhaler only at bedtime to reduce daily exposure

Answer

Use the inhaler only during acute symptom flares

Answer

Avoid using a spacer device to minimize oropharyngeal contact

Question 2

Which respiratory medication requires monitoring of serum drug levels due to its narrow therapeutic index?

Accepted Answer

Theophylline

Answer

Albuterol

Answer

Ipratropium

Answer

Fluticasone

Question 3

A COPD patient on triple therapy reports increased dyspnea and purulent yellow-green sputum for 3 days. This presentation is MOST consistent with:

Accepted Answer

Acute COPD exacerbation

Answer

Asthma-COPD overlap syndrome

Answer

New-onset community-acquired pneumonia

Answer

Medication-induced bronchospasm

Question 4

When counseling a patient about proper dry powder inhaler (DPI) technique, the pharmacist should emphasize:

Accepted Answer

Rapid, forceful inhalation through the device

Answer

Slow, gentle inhalation to avoid wasting the dose

Answer

Actuating the device before opening the mouth

Answer

Exhaling forcefully into the device before inhalation

Question 5

Which biologic agent targets the IL-4/IL-13 pathway and is FDA-approved for moderate-to-severe eosinophilic or OCS-dependent asthma?

Accepted Answer

Dupilumab (anti-IL-4Rα)

Answer

Omalizumab (anti-IgE)

Answer

Mepolizumab (anti-IL-5)

Answer

Benralizumab (anti-IL-5Rα)

Question 6

A patient has allergic asthma with serum IgE of 450 IU/mL, positive allergen skin testing, and remains uncontrolled on high-dose ICS/LABA. Which biologic is MOST appropriate?

Accepted Answer

Omalizumab (anti-IgE)

Answer

Benralizumab (anti-IL-5 receptor)

Answer

Mepolizumab (anti-IL-5)

Answer

Tezepelumab (anti-TSLP)

Question 7

Which statement about pulmonary rehabilitation in COPD is MOST accurate?

Accepted Answer

It improves exercise capacity and quality of life but has not been shown to reduce mortality

Answer

It is only beneficial for patients with FEV1 < 30% predicted

Answer

It is contraindicated in patients who are current smokers

Answer

Significant benefits are primarily observed within the first 2 weeks of the program