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Pharmacology Flashcards

6 cards from real MFDS practice questions. Tap to flip, then mark Knew It or Still Learning โ€” missed cards come back until you master them.

Read the first 6 Pharmacology flashcards as text
  1. Articaine differs from other amide local anaesthetics in that it contains:

    Answer: A thiophene ring

    Articaine uniquely contains a thiophene ring instead of a benzene ring, which increases its lipid solubility and ability to diffuse through bone.

  2. The maximum recommended dose of lidocaine with adrenaline for a healthy adult is approximately:

    Answer: 7 mg/kg (max 500 mg)

    Lidocaine with adrenaline (epinephrine) has a maximum recommended dose of 7 mg/kg up to 500 mg in healthy adults, higher than plain lidocaine due to vasoconstriction.

  3. Which antibiotic is first-line for odontogenic infections in penicillin-allergic patients?

    Answer: Clindamycin

    Clindamycin is an appropriate first-line alternative for odontogenic infections in penicillin-allergic patients due to its excellent activity against streptococci and anaerobes.

  4. NSAIDs exert their analgesic effect primarily by inhibiting which enzyme?

    Answer: Cyclooxygenase (COX)

    NSAIDs inhibit cyclooxygenase (COX-1 and COX-2) enzymes, thereby blocking prostaglandin synthesis and reducing pain, inflammation and fever.

  5. Fluconazole is the drug of choice for treating which oral fungal infection?

    Answer: Oropharyngeal candidiasis

    Fluconazole, a triazole antifungal, is highly effective and well tolerated for oropharyngeal and oesophageal candidiasis, particularly in immunocompromised patients.

  6. Bisphosphonates inhibit bone resorption primarily by targeting:

    Answer: Osteoclasts

    Bisphosphonates bind to hydroxyapatite and are taken up by osteoclasts, inhibiting the mevalonate pathway and inducing osteoclast apoptosis.