Medical Laboratory Technician Exam FREE Medical Laboratory Technician Blood Banking and Transfusion Questions and Answers 2

Question 1

A patient with blood type AB positive requires a platelet transfusion, but only type O platelets are available. What is the primary concern with this transfusion?

Accepted Answer

Anti-A and anti-B antibodies in the donor plasma may cause hemolysis

Answer

The platelets will be immediately destroyed by the recipient's immune system

Answer

Rh incompatibility will trigger an acute hemolytic reaction

Answer

There is no concern because platelets do not carry ABO antigens

Question 2

During an antibody identification panel, a technologist notices that all panel cells positive for the Jka antigen are reactive. The autocontrol is negative. Which additional test would best confirm anti-Jka?

Accepted Answer

Enzyme-treated panel cells

Answer

Ficin-treated panel cells to destroy Jka antigen

Answer

Cord blood cells

Answer

Neutralization with soluble Jka substance

Question 3

A crossmatch is incompatible at the antihuman globulin (AHG) phase. The antibody screen is negative. What is the most likely cause?

Accepted Answer

An antibody directed against a low-frequency antigen on the donor cells

Answer

ABO incompatibility between donor and recipient

Answer

A cold autoantibody interfering at 37°C

Answer

Contamination of the reagent red cells

Question 4

Which of the following is the most appropriate product for a neonate requiring an exchange transfusion for hemolytic disease of the fetus and newborn (HDFN) caused by anti-D?

Accepted Answer

Group O, Rh-negative red blood cells resuspended in AB plasma

Answer

Group O, Rh-positive red blood cells in saline

Answer

Mother's own red blood cells, washed

Answer

Group-specific Rh-negative whole blood

Question 5

A blood bank technologist performs a DAT on a post-transfusion sample and obtains a mixed-field reaction. What does this finding most likely indicate?

Accepted Answer

Circulating transfused donor cells are being coated with recipient antibody in vivo

Answer

The patient has a cold autoantibody

Answer

The polyspecific AHG reagent is contaminated

Answer

The patient has a positive DAT due to drug-induced antibody

Question 6

Which storage lesion change is most significant in red blood cells stored beyond 35 days in CPDA-1?

Accepted Answer

Decreased 2,3-DPG levels causing increased oxygen affinity

Answer

Increased ATP levels

Answer

Decreased potassium concentration in the supernatant

Answer

Improved red cell deformability

A patient with blood type AB positive requires a platelet transfusion, but only type O platelets are available.What is the primary concern with this transfusion?

A patient with blood type AB positive requires a platelet transfusion, but only type O platelets are available.
What is the primary concern with this transfusion?