ICVA Feline Pharmacology and Toxicology 2

Question 1

Which analgesic is contraindicated in cats due to glucuronidation deficiency leading to hepatotoxicity?

Accepted Answer

Acetaminophen

Answer

Buprenorphine

Answer

Meloxicam

Answer

Tramadol

Question 2

What is the mechanism by which permethrin causes toxicity in cats but not dogs?

Accepted Answer

Cats have more sensitive sodium channels in neurons

Answer

Cats absorb more dermally

Answer

Cats lack CYP450 enzymes to metabolize pyrethroids

Answer

Cats have a lower volume of distribution

Question 3

A cat presents with hypersalivation, muscle tremors, and hyperthermia after flea treatment. Which toxin is most likely?

Accepted Answer

Permethrin

Answer

Fipronil

Answer

Imidacloprid

Answer

Selamectin

Question 4

Which opioid is most commonly used in cats for perioperative analgesia due to its partial agonist properties and lower abuse potential?

Accepted Answer

Buprenorphine

Answer

Morphine

Answer

Fentanyl

Answer

Hydromorphone

Question 5

What is the recommended treatment for permethrin toxicosis in cats?

Accepted Answer

Bathing, IV fluids, diazepam or methocarbamol for tremors

Answer

Activated charcoal only

Answer

Methylene blue

Answer

Atropine and pralidoxime

Question 6

Which NSAID is approved for short-term use in cats in the United States for post-operative pain?

Accepted Answer

Robenacoxib

Answer

Carprofen

Answer

Meloxicam

Answer

Ketoprofen

Question 7

Cats are particularly sensitive to the toxic effects of benzocaine because it can cause which condition?

Accepted Answer

Methemoglobinemia

Answer

Nephrotoxicity

Answer

Hepatotoxicity

Answer

Cardiomyopathy