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Pharmacology and Toxicology Flashcards

6 cards from real IBCLC practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

Read the first 6 Pharmacology and Toxicology flashcards as text

  1. Which resource is considered the gold standard for evaluating medication safety during lactation?

    Answer: LactMed database and Hale's Medications and Mothers' Milk

    LactMed and Hale's are the most authoritative, evidence-based resources for evaluating drug safety during lactation.

  2. A breastfeeding mother needs a diagnostic procedure using gadolinium-based contrast for an MRI. What is the recommendation?

    Answer: Breastfeeding can continue without interruption as less than 0.04% of gadolinium is excreted in breast milk

    The amount of gadolinium excreted into breast milk is extremely small, making it safe to continue breastfeeding.

  3. Which class of antidepressants is generally considered most compatible with breastfeeding?

    Answer: Selective serotonin reuptake inhibitors (SSRIs), particularly sertraline and paroxetine

    SSRIs, particularly sertraline and paroxetine, have the most extensive safety data during breastfeeding.

  4. A mother who is a regular cannabis user asks about the safety of breastfeeding. What should the IBCLC advise?

    Answer: THC is lipophilic, concentrates in breast milk, is stored in infant fat tissue, and may affect neurodevelopment; abstaining is recommended

    THC is highly lipophilic, concentrates in breast milk at levels up to 8 times maternal plasma, and may affect neurodevelopment.

  5. What is the relative infant dose (RID) and what threshold is generally considered acceptable?

    Answer: RID is the percentage of the maternal weight-adjusted dose received by the infant through breast milk; less than 10% is generally acceptable

    The RID expresses the infant's dose as a percentage of the mother's weight-adjusted dose, with less than 10% generally considered acceptable.

  6. A breastfeeding mother is prescribed radioactive iodine (I-131) for thyroid ablation. What is the correct advice?

    Answer: Breastfeeding must be permanently discontinued for this infant as I-131 concentrates in breast milk and the thyroid of the breastfed infant

    Radioactive I-131 concentrates in breast milk and in the infant's thyroid gland, posing serious radiation risk.