GI GI Disorders and Diseases 3

Question 1

In irritable bowel syndrome (IBS), which diagnostic criteria are currently used?

Accepted Answer

Rome IV criteria

Answer

Manning criteria

Answer

Truelove-Witts criteria

Answer

Harvey-Bradshaw index

Question 2

Peutz-Jeghers syndrome is characterized by GI hamartomatous polyps and mucocutaneous pigmentation, and carries increased risk of malignancy in which gene mutation?

Accepted Answer

STK11 (LKB1) gene

Answer

APC gene

Answer

MLH1/MSH2 (mismatch repair genes)

Answer

SMAD4 gene

Question 3

Which of the following features distinguishes acute mesenteric ischemia from other causes of acute abdomen?

Accepted Answer

Pain out of proportion to physical exam findings

Answer

Severe rebound tenderness at onset

Answer

Diarrhea preceding pain

Answer

Normal WBC count

Question 4

Hereditary hemochromatosis most commonly results from a mutation in which gene, leading to iron overload and hepatic cirrhosis?

Accepted Answer

HFE

Answer

CFTR

Answer

ATP7B

Answer

SERPINA1

Question 5

Which type of viral hepatitis is transmitted via the fecal-oral route and does NOT cause chronic infection?

Accepted Answer

Hepatitis A

Answer

Hepatitis B

Answer

Hepatitis C

Answer

Hepatitis D

Question 6

A patient presents with watery diarrhea, hypokalemia, and achlorhydria (WDHA syndrome). Which tumor is most likely?

Accepted Answer

VIPoma

Answer

Gastrinoma

Answer

Insulinoma

Answer

Glucagonoma