FREE Medical Laboratory Technician Immunology and Serology Questions and Answers

Question 1

A patient presents with severe allergies, including hay fever and asthma. An elevation of which immunoglobulin class is most strongly associated with this type of Type I hypersensitivity reaction?

Accepted Answer

IgE

Answer

IgA

Answer

IgG

Answer

IgM

Question 2

A 19-year-old college student presents with fatigue, sore throat, and lymphadenopathy. A monospot test for heterophile antibodies is positive. This result is most consistent with an acute infection caused by which of the following viruses?

Accepted Answer

Epstein-Barr virus (EBV)

Answer

Cytomegalovirus (CMV)

Answer

Rubella virus

Answer

Varicella-zoster virus (VZV)

Question 3

In a sandwich enzyme-linked immunosorbent assay (ELISA) designed to detect a specific antigen, what is the final component added that directly interacts with an enzyme to produce a measurable color change?

Accepted Answer

A chromogenic substrate

Answer

The patient's antigen

Answer

A secondary (detection) antibody

Answer

A capture antibody

Question 4

The classical pathway of the complement system is primarily initiated by the binding of C1q to which of the following?

Accepted Answer

Antigen-antibody complexes

Answer

Bacterial endotoxins (LPS)

Answer

Mannose-binding lectin on pathogen surfaces

Answer

Spontaneously hydrolyzed C3

Question 5

A medical laboratory technician performs a Rapid Plasma Reagin (RPR) test on a patient's serum. The test slide shows visible black clumps against the white background of the card. How should this result be interpreted?

Accepted Answer

Reactive, indicating the presence of non-treponemal (reagin) antibodies

Answer

Non-reactive, indicating the absence of treponemal antibodies

Answer

Invalid, as the carbon particles have precipitated

Answer

Positive for neurosyphilis

Question 6

A physician suspects a patient has systemic lupus erythematosus (SLE). While an ANA test is a sensitive screening test, which of the following autoantibodies is considered highly specific for SLE and is a key component of its diagnostic criteria?

Accepted Answer

Anti-double-stranded DNA (anti-dsDNA)

Answer

Rheumatoid Factor (RF)

Answer

Anti-mitochondrial antibody (AMA)

Answer

Anti-cyclic citrullinated peptide (Anti-CCP)

A patient presents with severe allergies, including hay fever and asthma.An elevation of which immunoglobulin class is most strongly associated with this type of Type I hypersensitivity reaction?

A patient presents with severe allergies, including hay fever and asthma.
An elevation of which immunoglobulin class is most strongly associated with this type of Type I hypersensitivity reaction?