ExCPT Test Pharmacology 3

Question 1

Which drug class is primarily used to treat Type 2 diabetes by increasing insulin sensitivity in peripheral tissues?

Accepted Answer

Thiazolidinediones

Answer

Sulfonylureas

Answer

DPP-4 inhibitors

Answer

Alpha-glucosidase inhibitors

Question 2

A patient is prescribed atorvastatin. What is the primary mechanism of action of this drug?

Accepted Answer

Inhibits HMG-CoA reductase

Answer

Inhibits bile acid reabsorption

Answer

Activates LDL receptors directly

Answer

Inhibits cholesterol absorption in the gut

Question 3

Which of the following opioid analgesics has the HIGHEST risk of causing QT prolongation?

Accepted Answer

Methadone

Answer

Morphine

Answer

Hydrocodone

Answer

Oxycodone

Question 4

Benzodiazepines exert their anxiolytic effects by acting on which receptor?

Accepted Answer

GABA-A receptor

Answer

NMDA glutamate receptor

Answer

Serotonin 5-HT1A receptor

Answer

Dopamine D2 receptor

Question 5

Which drug is used as an antidote for acetaminophen (Tylenol) overdose?

Accepted Answer

N-acetylcysteine

Answer

Flumazenil

Answer

Naloxone

Answer

Atropine

Question 6

What is the primary pharmacological effect of selective serotonin reuptake inhibitors (SSRIs)?

Accepted Answer

Inhibit the reuptake of serotonin at the presynaptic terminal

Answer

Block dopamine reuptake in the prefrontal cortex

Answer

Directly stimulate postsynaptic serotonin receptors

Answer

Prevent serotonin breakdown by MAO enzymes