Pharmacist Flashcards
7 cards from real DHA practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 Pharmacist flashcards as text
A patient with a creatinine clearance of 25 mL/min is prescribed a renally cleared antibiotic. What dose adjustment strategy is most appropriate?
Answer: Reduce the dose, extend the dosing interval, or both
For renally cleared drugs, dose reduction and/or interval extension is necessary in renal impairment to prevent drug accumulation and toxicity.
Which controlled substance schedule under UAE law includes drugs with accepted medical use but high potential for abuse, such as morphine?
Answer: Table I (First Schedule)
Under UAE Federal Law No. 14 of 1995, morphine and similar opioids are classified under the First Schedule (Table I), which governs narcotics with strict prescribing requirements.
A pharmacist receives a prescription for sildenafil for a patient who is also taking isosorbide mononitrate. What should the pharmacist do?
Answer: Refuse to dispense sildenafil and contact the prescriber immediately
The combination of PDE5 inhibitors with nitrates is absolutely contraindicated due to severe hypotension risk; the pharmacist must withhold dispensing and contact the prescriber.
What is the primary advantage of using the AUC (area under the concentration-time curve) to measure drug exposure?
Answer: It provides a measure of total systemic drug exposure over time
AUC represents the total drug exposure over time and is used to compare bioavailability, calculate clearance, and guide dosing decisions.
A patient taking lithium for bipolar disorder is started on hydrochlorothiazide. What monitoring is most critical?
Answer: Serum lithium levels for toxicity
Thiazide diuretics reduce renal sodium and lithium excretion, increasing lithium serum levels and the risk of lithium toxicity.
Under DHA guidelines, which of the following must be documented in a pharmacy's dispensing record for a controlled substance?
Answer: Prescriber's name, drug name, quantity dispensed, patient identity, and prescription date
DHA and UAE regulations require comprehensive documentation for controlled substance dispensing, including prescriber details, patient identification, drug particulars, and date to ensure traceability.
Which of the following best describes 'therapeutic substitution' in pharmacy practice?
Answer: Replacing a prescribed drug with a pharmacologically similar drug from a different chemical class
Therapeutic substitution involves replacing a prescribed drug with a therapeutically equivalent agent from a different chemical class, which requires prescriber authorization.