Practice Test Geeks(CTP) Certified Transplant Preservationist Practice Test
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Organ Preservation Techniques Flashcards

7 cards from real CTP practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

Read the first 7 Organ Preservation Techniques flashcards as text

  1. What is the primary purpose of flushing organs with cold preservation solution immediately after cross-clamp?

    Answer: Rapidly cool the organ and wash out blood to halt metabolism

    Rapid cooling with preservation flush halts metabolic activity and removes blood that would otherwise clot or cause hypoxic injury.

  2. In ex vivo lung perfusion (EVLP), a PO₂/FiO₂ ratio greater than which value generally indicates acceptable lung function for transplant?

    Answer: 400 mmHg

    A PaO₂/FiO₂ ratio >400 mmHg on EVLP is considered a threshold for acceptable oxygenation function prior to transplantation.

  3. Which of the following best describes 'primary graft dysfunction' (PGD) in lung transplantation and its relationship to preservation?

    Answer: Ischemia-reperfusion injury causing acute lung injury within 72 hours post-transplant

    PGD is a form of ischemia-reperfusion injury that manifests as acute lung injury within 72 hours and is directly linked to preservation quality.

  4. Which preservation technique is most appropriate for a marginal kidney from an older DCD donor to maximize viability assessment?

    Answer: Hypothermic machine perfusion (HMP) with viability monitoring

    HMP allows continuous viability monitoring (flow, resistance, lactate) for marginal DCD kidneys while also reducing ischemic injury.

  5. What is the significance of 'back-table preparation' during organ transplantation?

    Answer: Trimming and preparing the organ's vasculature for anastomosis while maintaining cold storage

    Back-table preparation involves trimming excess tissue, ligating accessory vessels, and preparing vascular cuffs while keeping the organ cold to minimize warm ischemia.

  6. Which component distinguishes Institut Georges Lopez-1 (IGL-1) preservation solution from University of Wisconsin solution?

    Answer: IGL-1 uses polyethylene glycol (PEG) as the colloid instead of hydroxyethyl starch

    IGL-1 replaces UW's hydroxyethyl starch with polyethylene glycol, which has immunomodulatory properties in addition to oncotic effects.

  7. During organ procurement, why is the aorta cross-clamped before initiating preservation flush?

    Answer: To isolate the abdominal viscera from cardiac output and allow targeted cold perfusion

    Cross-clamping the aorta stops warm blood flow to the organs and directs cold preservation solution exclusively to the abdominal or thoracic organs being procured.