CPJE Sterile Products and IV Admixtures Flashcards

Under California law, a pharmacy compounding sterile preparations for office use must:

Answer: Hold a sterile compounding pharmacy license from the Board of Pharmacy

California requires pharmacies engaged in sterile compounding, including office-use preparations, to obtain a separate sterile compounding pharmacy license.

Which solution is an appropriate diluent for intravenous vancomycin administration?

Answer: 0.9% sodium chloride (NS) or 5% dextrose in water (D5W)

Vancomycin is compatible with NS and D5W for IV infusion; bacteriostatic solutions are avoided for large-volume IV preparations.

What is the recommended minimum infusion time for vancomycin 1g IV to prevent Red Man Syndrome?

Answer: At least 60 minutes

Vancomycin must be infused over at least 60 minutes per gram to prevent Red Man Syndrome, an infusion-related reaction.

A pharmacist identifies a physical incompatibility between two IV medications. What should be done?

Answer: Administer the drugs through separate IV lines or at separate times

Physical incompatibilities such as precipitation or color change indicate the drugs must be separated to ensure safety and therapeutic integrity.

Which type of container is required for light-sensitive IV preparations such as nitroglycerin infusions?

Answer: Amber or opaque IV bags and tubing

Light-sensitive drugs like nitroglycerin must be protected using amber or opaque containers throughout preparation and administration.

Environmental monitoring in a sterile compounding facility includes surface sampling using what primary method?

Answer: Contact plates or swabs with growth media incubated for colony-forming unit counts

USP requires regular surface sampling with contact plates or swabs incubated for microbial growth to detect contamination in the cleanroom.