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Infection Control & Prevention Flashcards

7 cards from real CPI practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

Read the first 7 Infection Control & Prevention flashcards as text

  1. In a clinical trial, a participant develops a catheter-associated urinary tract infection (CAUTI). Which organism is most commonly implicated in CAUTIs?

    Answer: Escherichia coli

    E. coli is the most common causative pathogen in catheter-associated urinary tract infections.

  2. A researcher notices that trial staff are not consistently performing hand hygiene between participant contacts. The MOST effective immediate intervention is:

    Answer: Install alcohol-based hand rub dispensers at point-of-care

    Point-of-care placement of alcohol-based hand rub dispensers is the most effective environmental intervention to improve hand hygiene compliance.

  3. Which of the following blood-borne pathogens has the highest transmission risk after a needlestick injury from an infected source?

    Answer: Hepatitis B virus (HBV)

    HBV has the highest transmission risk per needlestick (~30%), compared to ~3% for HCV and ~0.3% for HIV.

  4. A clinical trial site receives a shipment of investigational vaccines requiring storage at 2–8°C. Upon arrival, the refrigerator temperature log shows an excursion to 12°C overnight. The PI should FIRST:

    Answer: Quarantine the vaccines and contact the sponsor

    Vaccines affected by a temperature excursion must be quarantined and the sponsor contacted to assess viability before any use or disposal.

  5. Standard Precautions in a clinical research setting apply to:

    Answer: All blood and body fluids regardless of diagnosis

    Standard Precautions assume all blood and body fluids are potentially infectious and apply to every participant regardless of known infection status.

  6. In the context of clinical research, which action BEST reduces the risk of cross-contamination between investigational product preparations?

    Answer: Using dedicated preparation areas and cleaning between uses

    Dedicated preparation areas with cleaning between uses physically prevent cross-contamination of investigational products.

  7. A participant in an oncology trial develops febrile neutropenia. Which infection control measure is MOST critical to implement immediately?

    Answer: Protective (Reverse) Isolation

    Protective (reverse) isolation protects severely immunocompromised patients from environmental pathogens that would not harm immunocompetent individuals.