Compounding Flashcards
7 cards from real CPHT practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 Compounding flashcards as text
Which type of water is required for reconstituting parenteral preparations in sterile compounding?
Answer: Sterile Water for Injection USP
Sterile Water for Injection (SWFI) USP is the standard diluent for parenteral products because it is both purified and rendered sterile and pyrogen-free.
A compounded transdermal gel is prepared using PLO (pluronic lecithin organogel). The purpose of PLO is to:
Answer: Enhance penetration of the drug through the skin
PLO is a lipophilic gel base that facilitates transdermal drug absorption by improving drug penetration through the stratum corneum.
Before discarding a returned or unused compounded hazardous drug preparation, the pharmacy technician should:
Answer: Dispose of it via an EPA-compliant pharmaceutical waste vendor or reverse distributor
Hazardous drug waste must be disposed of through regulated channels (e.g., Pharmaceutical Waste Rule-compliant containers and vendors) to protect public and environmental health.
Osmolarity is a critical parameter when compounding ophthalmic preparations because:
Answer: Solutions outside the isotonic range (approximately 285–310 mOsm/L) cause irritation or damage to ocular tissue
Ophthalmic preparations must be near isotonic (approximately 285–310 mOsm/L) to avoid pain, irritation, and cellular damage to the delicate eye tissues.
Which of the following represents a correct first-air principle when working inside a laminar airflow workbench (LAFW)?
Answer: Never allow any object to interrupt the unidirectional airflow path between the HEPA filter and an open critical site
First-air is the uncontaminated air directly from the HEPA filter; no object, including hands, should block this air from reaching an open vial, needle, or syringe tip.
A technician is compounding a preparation that calls for 'qs ad 120 mL.' The preparation already contains 85 mL of liquid ingredients. How much solvent should be added?
Answer: 35 mL
'Qs ad 120 mL' means add sufficient quantity of solvent to make the total volume 120 mL; 120 − 85 = 35 mL.
According to USP , personnel who compound sterile preparations must perform hand hygiene and garbing in which order?
Answer: Hand hygiene → shoe covers → head cover → mask → gown → gloves
USP specifies garbing from the most contaminated (feet) to the least contaminated (hands/gloves) areas: shoe covers, head cover, mask/face shield, gown, then hand hygiene and sterile gloves last.