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CMT Blood Banking and Transfusion Medicine Flashcards

6 cards from real CMT practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

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  1. Which ABO blood group is considered the 'universal donor' for red blood cell transfusions?

    Answer: O

    Group O red blood cells lack A and B antigens, making them compatible with recipients of any ABO blood group in emergency situations.

  2. The Rh blood group antigen most commonly responsible for hemolytic disease of the fetus and newborn (HDFN) is:

    Answer: Rh(D)

    The D antigen is the most immunogenic Rh antigen; Rh(D)-negative mothers who form anti-D antibodies pose the greatest risk for severe HDFN.

  3. A direct antiglobulin test (DAT) is used to detect:

    Answer: Antibodies coating the patient's red blood cells in vivo

    The DAT (direct Coombs test) uses anti-human globulin to detect IgG antibodies or complement already bound to circulating red blood cells.

  4. Platelet concentrates should be stored at:

    Answer: 20–24°C with continuous agitation

    Platelets must be stored at room temperature (20–24°C) with constant agitation to maintain viability and prevent aggregation; refrigeration activates and damages platelets.

  5. Which crossmatch technique detects most clinically significant alloantibodies that may cause hemolytic transfusion reactions?

    Answer: Antihuman globulin (AHG) crossmatch

    The AHG crossmatch (indirect Coombs phase) detects IgG alloantibodies that react at 37°C and are associated with hemolytic reactions.

  6. Fresh frozen plasma (FFP) is indicated for:

    Answer: Replacement of coagulation factors in a bleeding patient with multiple factor deficiencies

    FFP contains all coagulation factors and is indicated for bleeding patients with documented factor deficiencies, liver disease-related coagulopathy, or massive transfusion.