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CMT Blood Banking and Transfusion Medicine Flashcards

6 cards from real CMT practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

Read the first 6 CMT Blood Banking and Transfusion Medicine flashcards as text

  1. Which compatibility testing phase is omitted when a patient has a negative antibody screen and no history of clinically significant antibodies?

    Answer: Antihuman globulin (AHG) crossmatch phase

    Current AABB standards allow an electronic or immediate-spin crossmatch (omitting the AHG phase) when the antibody screen is negative and no prior alloantibodies are on record.

  2. A patient with blood group A has which naturally occurring antibodies?

    Answer: Anti-B

    A person with blood group A naturally produces anti-B antibodies, while group B individuals have anti-A; group O individuals have both anti-A and anti-B.

  3. Leukoreduction of blood products is used primarily to reduce the risk of:

    Answer: Febrile non-hemolytic transfusion reactions and CMV transmission

    Removing white blood cells (leukoreduction) reduces the cytokines and CMV-infected lymphocytes that cause febrile non-hemolytic reactions and CMV transmission.

  4. Transfusion-related acute lung injury (TRALI) is primarily caused by:

    Answer: Donor anti-HLA or anti-neutrophil antibodies reacting with recipient leukocytes

    TRALI is an immune-mediated reaction where donor antibodies (anti-HLA or anti-HNA) activate recipient neutrophils in the pulmonary vasculature, causing acute respiratory distress within 6 hours of transfusion.

  5. Which additive in blood collection tubes for coagulation studies (PT/aPTT) acts as an anticoagulant by binding calcium?

    Answer: Sodium citrate

    Sodium citrate (blue-top tube) chelates calcium ions, reversibly inhibiting the coagulation cascade and preserving clotting factor activity for PT/aPTT testing.

  6. When a blood bank technologist discovers a discrepancy between forward and reverse ABO grouping, the FIRST action should be:

    Answer: Repeat testing with fresh reagents and a new patient sample

    ABO discrepancies must be resolved before issuing blood; repeating the test with fresh reagents and a new sample rules out technical errors as the first step in the investigation.