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CMT Blood Banking and Transfusion Medicine Flashcards

6 cards from real CMT practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

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  1. A transfusion reaction presenting with fever, chills, and flank pain minutes after starting a transfusion most suggests:

    Answer: Acute hemolytic transfusion reaction

    Fever, chills, and flank pain (from renal involvement) occurring rapidly after transfusion onset are classic signs of an acute hemolytic transfusion reaction due to ABO incompatibility.

  2. Which test is performed to detect unexpected alloantibodies in a patient's plasma before transfusion?

    Answer: Antibody screen (indirect antiglobulin test)

    The antibody screen (indirect antiglobulin test) tests the patient's serum against reagent red cells expressing known antigens to detect unexpected alloantibodies.

  3. Cryoprecipitate is the product of choice for which deficiency?

    Answer: Fibrinogen deficiency or von Willebrand disease

    Cryoprecipitate is rich in fibrinogen, Factor VIII, von Willebrand factor, and Factor XIII, making it the preferred product for fibrinogen deficiency and vWD.

  4. Irradiation of blood products is performed primarily to prevent:

    Answer: Transfusion-associated graft-versus-host disease (TA-GvHD)

    Gamma irradiation inactivates donor T lymphocytes in blood products, preventing them from engrafting and attacking the immunocompromised recipient in TA-GvHD.

  5. The Kleihauer-Betke test is used to:

    Answer: Detect fetal-maternal hemorrhage by quantifying fetal cells in maternal blood

    The Kleihauer-Betke acid elution test differentiates fetal (HbF-containing) from adult red cells in maternal blood to estimate the degree of feto-maternal hemorrhage and guide Rh immunoglobulin dosing.

  6. The maximum storage time for packed red blood cells (pRBCs) in CPDA-1 additive solution at 1–6°C is:

    Answer: 35 days

    pRBCs stored in CPDA-1 solution have a shelf life of 35 days at 1–6°C; extended additive solutions (AS-1, AS-3, AS-5) extend storage to 42 days.