Practice Test Geeks(CLT) Clinical Laboratory Technologist Certification Practice Test
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Treatment Protocols & Procedures Flashcards

7 cards from real CLT practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

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  1. A patient on warfarin therapy has an INR of 5.8 with no active bleeding. What is the most appropriate initial management?

    Answer: Hold warfarin and monitor closely

    For supratherapeutic INR without bleeding, holding warfarin and monitoring is the first-line approach before considering vitamin K.

  2. Which blood component is the MOST appropriate for a patient with isolated factor VIII deficiency (hemophilia A)?

    Answer: Cryoprecipitate

    Cryoprecipitate is rich in factor VIII, fibrinogen, von Willebrand factor, and factor XIII, making it preferred for hemophilia A treatment.

  3. A patient requires a blood transfusion but has a known history of febrile non-hemolytic transfusion reactions. What modification to the transfusion should be made?

    Answer: Use leukoreduced blood products

    Leukoreduction removes white blood cells that cause febrile non-hemolytic reactions by releasing cytokines during storage.

  4. In disseminated intravascular coagulation (DIC), which laboratory finding combination is most characteristic?

    Answer: Prolonged PT/PTT, low fibrinogen, elevated D-dimer

    DIC is characterized by consumption of clotting factors (prolonged PT/PTT), fibrinogen depletion, low platelets, and elevated D-dimer from fibrin degradation.

  5. Which electrolyte imbalance is most commonly associated with massive blood transfusion and requires monitoring?

    Answer: Hypocalcemia

    Citrate in stored blood products chelates calcium, causing hypocalcemia during massive transfusion, especially when the liver cannot metabolize citrate fast enough.

  6. A patient with type O-negative blood receives an incompatible crossmatch transfusion. Which finding would FIRST indicate an acute hemolytic transfusion reaction?

    Answer: Fever and chills

    Fever and chills are typically the earliest signs of an acute hemolytic transfusion reaction, prompting immediate investigation.

  7. For therapeutic phlebotomy in hereditary hemochromatosis, what is the standard volume removed per session in most protocols?

    Answer: 450–500 mL

    Standard therapeutic phlebotomy removes approximately 450–500 mL (equivalent to one unit of blood) per session to reduce iron stores.