Research Methods & Evidence-Based Practice Flashcards
7 cards from real CET practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 Research Methods & Evidence-Based Practice flashcards as text
In a randomized controlled trial evaluating a new echocardiographic protocol, which element is MOST critical for minimizing selection bias?
Answer: Random allocation of participants to groups
Random allocation ensures that known and unknown confounders are evenly distributed between groups, directly minimizing selection bias.
A meta-analysis of studies on diastolic dysfunction grading reports high statistical heterogeneity (I²=85%). What does this indicate?
Answer: There is significant variability in results across studies
An I² of 85% indicates substantial heterogeneity, meaning the variability in study results is greater than expected by chance alone.
Which study design is BEST suited to determine the incidence of new-onset atrial fibrillation detected by echocardiography in a healthy population over 10 years?
Answer: Prospective cohort study
A prospective cohort study follows a disease-free population over time, making it ideal for measuring incidence of new conditions.
When applying evidence-based practice, a CET finds a Level I systematic review and a Level III expert opinion supporting different LVEF measurement techniques. Which should guide practice?
Answer: The systematic review, as it represents the highest level of evidence
Level I systematic reviews sit at the top of the evidence hierarchy and should take precedence over expert opinion in guiding clinical practice.
A study reports that 3D echocardiography has a sensitivity of 92% and specificity of 88% for detecting apical thrombus. What does specificity of 88% mean?
Answer: 88% of patients without thrombus were correctly identified as negative
Specificity is the ability of a test to correctly identify true negatives — patients who do not have the condition.
Which statistical measure is used to express the precision of a sample mean and is commonly reported in echocardiographic measurement studies?
Answer: Standard error of the mean
The standard error of the mean (SEM) quantifies how precisely the sample mean estimates the population mean.
A new guideline on mitral regurgitation grading is published. According to evidence-based practice principles, what is the FIRST step a CET should take?
Answer: Critically appraise the guideline for validity and applicability
Critical appraisal of the guideline's methodology and applicability to one's patient population is the first EBP step before implementation.