Dialyzer Reprocessing and Reuse Flashcards
6 cards from real CHT practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 6 Dialyzer Reprocessing and Reuse flashcards as text
Which type of dialyzer membrane is most commonly used in modern hemodialysis and associated with improved biocompatibility?
Answer: High-flux synthetic (polysulfone, polyethersulfone)
High-flux synthetic membranes like polysulfone offer superior biocompatibility, higher middle-molecule clearance, and lower complement activation compared to cellulosic membranes.
The ultrafiltration coefficient (KUF) of a dialyzer describes:
Answer: The amount of fluid removed per mmHg transmembrane pressure per hour
KUF measures dialyzer water permeability: milliliters of fluid transferred per hour per mmHg of transmembrane pressure, distinguishing low-flux from high-flux dialyzers.
First-use syndrome (type A anaphylactic reaction) during hemodialysis is most classically associated with which dialyzer membrane type?
Answer: Ethylene oxide-sterilized AN69 membranes in patients on ACE inhibitors
AN69 membranes can adsorb blood contact factor XII activating bradykinin, and ACE inhibitors prevent bradykinin breakdown, causing severe anaphylactic reactions.
Reuse of dialyzers in the United States is regulated by which federal agency?
Answer: CMS (Centers for Medicare & Medicaid Services) via Conditions for Coverage
CMS regulates dialyzer reuse through the ESRD Conditions for Coverage, requiring facilities to follow AAMI standards for safe reprocessing practices.
The primary reason high-flux dialyzers require ultrapure dialysate is:
Answer: Their large pore size allows back-filtration of dialysate into the blood compartment
High-flux membranes can allow dialysate to back-filter into the blood compartment due to transmembrane pressure gradients, making dialysate purity critical to prevent endotoxin transfer.
Which occupational exposure risk is greatest for staff performing manual dialyzer reprocessing without proper PPE?
Answer: Chemical exposure to germicides (formaldehyde, peracetic acid)
Staff performing dialyzer reprocessing face the greatest risk from chemical exposure to germicides like formaldehyde (carcinogen) and peracetic acid (corrosive), requiring proper PPE.