CAOP Sterile Products and Aseptic Technique

Question 1

Which USP chapter governs the compounding of sterile preparations in the United States?

Accepted Answer

USP <797>

Answer

USP <795>

Answer

USP <800>

Answer

USP <1160>

Question 2

What is the primary purpose of a laminar airflow workbench (LAFW) in sterile compounding?

Accepted Answer

To provide a particle-free ISO Class 5 environment for aseptic manipulation

Answer

To sterilize the final product by UV light

Answer

To maintain a negative-pressure environment

Answer

To detect pyrogens in injectable solutions

Question 3

Which route of administration requires the MOST stringent sterility requirements?

Accepted Answer

Intrathecal

Answer

Oral

Answer

Topical

Answer

Ophthalmic drops

Question 4

What does the term 'beyond-use date' (BUD) mean for a compounded sterile preparation?

Accepted Answer

The date after which the preparation must not be used, based on compounding conditions and storage

Answer

The manufacturer's expiration date

Answer

The date the preparation was ordered

Answer

The date by which the preparation must be dispensed

Question 5

A pharmacist is preparing a total parenteral nutrition (TPN) solution. Which electrolyte combination poses the greatest incompatibility risk?

Accepted Answer

Calcium and phosphate

Answer

Sodium chloride and dextrose

Answer

Magnesium sulfate and potassium chloride

Answer

Sodium acetate and multivitamins

Question 6

ISO Class 5 air quality is required in which compounding zone?

Accepted Answer

Direct compounding area (DCA) within the primary engineering control

Answer

General support area

Answer

Ante-room

Answer

Buffer room