Board Certified Ophthalmologist FREE Cornea and External Disease Questions and Answers 2

Question 1

A 45-year-old contact lens wearer presents with a rapidly progressive corneal ulcer and satellite lesions.
Culture on Sabouraud agar grows filamentous organisms.
Which antifungal agent is the most appropriate first-line treatment?

Accepted Answer

Natamycin 5% ophthalmic suspension

Answer

Fluconazole 0.2% ophthalmic drops

Answer

Amphotericin B 0.15% ophthalmic drops

Answer

Oral itraconazole

Question 2

Which layer of the cornea is most responsible for maintaining corneal deturgescence and transparency?

Accepted Answer

Corneal endothelium

Answer

Bowman layer

Answer

Corneal epithelium

Answer

Descemet membrane

Question 3

A patient with rheumatoid arthritis develops progressive corneal thinning with an overlying epithelial defect in the peripheral cornea. What is the most likely diagnosis?

Accepted Answer

Peripheral ulcerative keratitis

Answer

Mooren ulcer

Answer

Terrien marginal degeneration

Answer

Pellucid marginal degeneration

Question 4

A 30-year-old male presents with recurrent episodes of unilateral stromal keratitis with decreased corneal sensation. Examination reveals ghost vessels and stromal scarring. Which pathogen is most likely responsible?

Accepted Answer

Herpes simplex virus type 1

Answer

Varicella-zoster virus

Answer

Acanthamoeba species

Answer

Epstein-Barr virus

Question 5

During penetrating keratoplasty, the surgeon notes a positive Seidel test at one of the suture sites on the first postoperative day. The anterior chamber is well-formed. What is the most appropriate initial management?

Accepted Answer

Application of a bandage contact lens

Answer

Immediate return to operating room for resuturing

Answer

Observation without intervention

Answer

Cyanoacrylate tissue adhesive application

Question 6

Which corneal dystrophy is characterized by bilateral, progressive, asymmetric corneal ectasia with iron deposition in the epithelium forming a Fleischer ring?

Accepted Answer

Keratoconus

Answer

Posterior polymorphous corneal dystrophy

Answer

Fuchs endothelial corneal dystrophy

Answer

Granular corneal dystrophy

A 45-year-old contact lens wearer presents with a rapidly progressive corneal ulcer and satellite lesions.Culture on Sabouraud agar grows filamentous organisms.Which antifungal agent is the most appropriate first-line treatment?

A 45-year-old contact lens wearer presents with a rapidly progressive corneal ulcer and satellite lesions.
Culture on Sabouraud agar grows filamentous organisms.
Which antifungal agent is the most appropriate first-line treatment?