Infectious Disease and Immunization Management Flashcards
7 cards from real BCACP practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 Infectious Disease and Immunization Management flashcards as text
A patient with HIV on antiretroviral therapy has a CD4 count of 150 cells/μL. Which opportunistic infection prophylaxis is MOST indicated?
Answer: Trimethoprim-sulfamethoxazole for Pneumocystis jirovecii pneumonia
TMP-SMX prophylaxis for PCP is indicated when CD4 count falls below 200 cells/μL.
Which hepatitis B vaccine schedule is recommended for adults with diabetes mellitus aged 60 years or older?
Answer: Vaccination should be at the clinician's discretion based on risk
ACIP recommends hepatitis B vaccination for adults 19–59 with diabetes and at the clinician's discretion for those ≥60 years.
A patient is prescribed rifampin for latent TB. Which drug interaction requires the most urgent counseling?
Answer: Warfarin — reduced anticoagulant effect
Rifampin is a potent CYP450 inducer that significantly reduces warfarin levels, increasing thromboembolism risk.
Which statement best describes the role of oseltamivir in outpatient influenza management?
Answer: Most beneficial when initiated within 48 hours of symptom onset
Oseltamivir reduces duration and severity of influenza most effectively when started within 48 hours of symptom onset.
A 35-year-old pregnant woman at 28 weeks asks about Tdap vaccination. What is the correct guidance?
Answer: Administer Tdap during each pregnancy, preferably between 27–36 weeks gestation
ACIP recommends Tdap during every pregnancy, ideally at 27–36 weeks, to provide neonatal pertussis protection via maternal antibody transfer.
A patient with recurrent UTIs requests prophylaxis. Which regimen is evidence-based for continuous antibiotic prophylaxis?
Answer: Nitrofurantoin 50–100 mg daily at bedtime
Nitrofurantoin at low doses taken nightly is a well-established option for continuous prophylaxis of recurrent uncomplicated UTIs.
Which vaccine is CONTRAINDICATED in a patient receiving high-dose corticosteroids (prednisone ≥20 mg/day for >2 weeks)?
Answer: Live attenuated influenza vaccine (LAIV)
LAIV is a live vaccine contraindicated in immunocompromised patients, including those on high-dose systemic corticosteroids.