ASCP Transfusion Medicine 2

Question 1

The most clinically significant Rh antigen after D is:

Accepted Answer

c antigen (little c)

Answer

C antigen

Answer

E antigen

Answer

e antigen

Question 2

Cryoprecipitate is prepared from fresh frozen plasma (FFP) and is enriched for which components?

Accepted Answer

Fibrinogen, Factor VIII, vWF, Factor XIII, and fibronectin

Answer

Albumin and IgG

Answer

All coagulation factors equally

Answer

Platelets and Factor V

Question 3

Irradiation of blood products prevents:

Accepted Answer

Transfusion-associated graft-versus-host disease (TA-GvHD)

Answer

Bacterial contamination

Answer

CMV transmission

Answer

Alloimmunization to HLA antigens

Question 4

Kidd antibodies (anti-Jka, anti-Jkb) are clinically notorious because they:

Accepted Answer

Can become undetectable between transfusions, causing unexpected delayed hemolytic transfusion reactions

Answer

Cause strong immediate hemolysis always detectable on crossmatch

Answer

Are only IgM and activate complement weakly

Answer

React best at room temperature

Question 5

Which coagulation factor is present in fresh frozen plasma (FFP) but NOT in stored packed red blood cells?

Accepted Answer

Factor VIII

Answer

Factor VII

Answer

Factor X

Answer

Factor XIII

Question 6

In blood banking, what additional safety check does a crossmatch provide beyond a type and screen?

Accepted Answer

It serologically tests the specific donor unit against the patient's serum to detect incompatibility

Answer

It provides the patient's ABO and Rh type

Answer

It identifies all patient antibodies

Answer

It determines HLA compatibility