ASCP Laboratory Safety and Quality Control

Question 1

According to OSHA's Hazard Communication Standard, what must be present on all chemical containers in the histology laboratory?

Accepted Answer

GHS-compliant labels with hazard pictograms, signal word, and hazard statements

Answer

Technician initials only

Answer

A barcode and lot number

Answer

The manufacturer's name only

Question 2

What is the proper disposal method for used xylene in the histology laboratory?

Accepted Answer

Collect in labeled hazardous waste containers for licensed disposal

Answer

Pour down the drain with water

Answer

Evaporate in a fume hood

Answer

Neutralize with baking soda and discard

Question 3

What class of fire extinguisher should be used for a solvent (xylene/alcohol) fire in the histology lab?

Accepted Answer

Class B or BC (CO2 or dry chemical)

Answer

Class A (water-based)

Answer

Class D (metal fires)

Answer

Class K (cooking oils)

Question 4

What is the purpose of a Levey-Jennings chart in histology laboratory quality control?

Accepted Answer

Visually monitor control values over time to detect trends and shifts

Answer

Track reagent inventory

Answer

Record patient results

Answer

Schedule preventive maintenance

Question 5

Which personal protective equipment (PPE) is required when handling formalin-fixed specimens in the histology laboratory?

Accepted Answer

Gloves, lab coat, and eye protection at minimum

Answer

Gloves only

Answer

Only a face shield

Answer

No PPE required for fixed specimens

Question 6

What does CAP (College of American Pathologists) accreditation require regarding staining controls?

Accepted Answer

Each staining run must include appropriate positive and negative controls

Answer

Controls are optional if the lab has experienced staff

Answer

Controls are only required for IHC, not special stains

Answer

Controls must be run weekly, not on each batch