ASCP Laboratory Safety and Quality Control 3

Question 1

What does CAP checklist item require regarding the turnaround time (TAT) for surgical pathology specimens?

Accepted Answer

Laboratories must establish, monitor, and document TAT goals for different specimen types

Answer

There is no TAT requirement

Answer

TAT only applies to cytology specimens

Answer

TAT must be under 24 hours for all specimens

Question 2

What is the purpose of proficiency testing (PT) in clinical histology laboratories?

Accepted Answer

To externally validate laboratory performance by testing unknown samples against peer laboratories

Answer

To train new staff on staining techniques

Answer

To calibrate microtome blade angles

Answer

To verify reagent shelf life

Question 3

Under CLIA regulations, who is responsible for the overall operation and administration of a histology laboratory?

Accepted Answer

The laboratory director

Answer

The senior histotechnician

Answer

The hospital administrator

Answer

Each individual technician equally

Question 4

What is the standard recommended storage temperature for most unstained paraffin sections awaiting IHC testing?

Accepted Answer

Room temperature for up to a limited time; refrigeration (4°C) for longer storage

Answer

Room temperature for indefinite periods

Answer

Freezer (-20°C) always

Answer

Incubator at 37°C

Question 5

What is the role of internal quality controls in an H&E staining batch?

Accepted Answer

To verify that each staining run is performing within acceptable standards before patient slides are released

Answer

To replace the need for external proficiency testing

Answer

To document reagent purchases

Answer

To calibrate the automated stainer software

Question 6

Which regulatory body sets standards for quality systems in US clinical laboratories, including histology?

Accepted Answer

CLIA (administered by CMS), with accreditation from CAP or Joint Commission

Answer

FDA only

Answer

OSHA only

Answer

CDC only