ASCP Laboratory Safety and Quality Control 2

Question 1

What is the permissible exposure limit (PEL) for formaldehyde established by OSHA?

Accepted Answer

0.75 ppm (8-hour TWA)

Answer

5 ppm (8-hour TWA)

Answer

2 ppm (8-hour TWA)

Answer

0.1 ppm (8-hour TWA)

Question 2

When should an autoclave (steam sterilization) be used in the histology laboratory?

Accepted Answer

To decontaminate biohazardous waste and instruments

Answer

To sterilize paraffin blocks before sectioning

Answer

To dry processed tissue sections

Answer

To clear sections in preparation for staining

Question 3

What does a reagent QC failure on a negative control indicate?

Accepted Answer

Non-specific or background staining is present, suggesting a reagent or protocol problem

Answer

The positive control worked correctly

Answer

The staining run can be reported as valid

Answer

Tissue autolysis occurred

Question 4

In the context of laboratory safety, what is the purpose of a Safety Data Sheet (SDS)?

Accepted Answer

To provide comprehensive hazard, handling, storage, and emergency information for chemical substances

Answer

To record patient demographics

Answer

To document equipment maintenance

Answer

To track reagent expiration dates

Question 5

What is the minimum required documentation for each H&E staining run in an accredited laboratory?

Accepted Answer

Reagent lot numbers, dates, technician ID, and control results

Answer

No documentation required

Answer

Patient name only

Answer

Staining time and temperature only

Question 6

What action should be taken if a microtome blade injury occurs in the histology lab?

Accepted Answer

Immediately wash the wound, report to supervisor, and follow the exposure control plan

Answer

Continue working and report at the end of shift

Answer

Apply a bandage and document later

Answer

Only report if bleeding is severe