ASCP Immunohematology (Blood Banking) 3

Question 1

Which blood product requires irradiation to prevent transfusion-associated graft-versus-host disease (TA-GvHD)?

Accepted Answer

Cellular components (RBCs, platelets) for immunocompromised patients

Answer

Fresh frozen plasma

Answer

Cryoprecipitate

Answer

Albumin solutions

Question 2

Platelet concentrates should be stored at what temperature with continuous agitation?

Accepted Answer

20–24°C with continuous agitation

Answer

1–6°C without agitation

Answer

−18°C frozen

Answer

37°C in incubator

Question 3

An acute hemolytic transfusion reaction most commonly results from:

Accepted Answer

ABO incompatibility due to clerical error

Answer

Rh incompatibility

Answer

Bacterial contamination

Answer

Allergic reaction to plasma proteins

Question 4

Washed red blood cells are indicated for which patient population?

Accepted Answer

Patients with IgA deficiency who have anti-IgA antibodies

Answer

Patients with iron deficiency

Answer

Neonates receiving exchange transfusion only

Answer

Patients with sickle cell disease

Question 5

Which ABO blood type is the universal plasma donor?

Accepted Answer

Type AB

Answer

Type O

Answer

Type A

Answer

Type B

Question 6

The gel card (column agglutination) technology in blood banking works by:

Accepted Answer

Centrifuging cells through a dextran-acrylamide gel that traps agglutinated cells

Answer

Heating cells to detect cold antibodies

Answer

Adding lysins to detect complement fixation

Answer

Using flow cytometry to count agglutinated cells