AMC MCQ AMC MCQ - Australian Medical Council Multiple Choice Questions Infectious Diseases and Immunology Questions and Answers 2

Question 1

A 60-year-old renal transplant recipient presents with fever and a rising serum creatinine 3 months post-transplant. CMV antigenemia assay is positive. What is the treatment of choice?

Accepted Answer

Ganciclovir (IV) or valganciclovir (oral)

Answer

Acyclovir

Answer

Foscarnet

Answer

Cidofovir

Question 2

A 25-year-old presents with fever, sore throat, lymphadenopathy, and a positive heterophile antibody (Monospot) test. Which virus is responsible?

Accepted Answer

Epstein-Barr virus

Answer

Cytomegalovirus

Answer

Human herpesvirus 6

Answer

Adenovirus

Question 3

Which immunoglobulin class is primarily responsible for the secondary (anamnestic) immune response?

Accepted Answer

IgG

Answer

IgM

Answer

IgA

Answer

IgE

Question 4

A healthcare worker is exposed to a needlestick from an HBeAg-positive patient. The worker is unvaccinated. What is the most appropriate immediate management?

Accepted Answer

Hepatitis B immune globulin (HBIG) plus hepatitis B vaccination

Answer

Hepatitis B vaccination alone

Answer

Tenofovir prophylaxis

Answer

No intervention needed

Question 5

Deficiency of which complement protein predisposes to recurrent Neisseria infections?

Accepted Answer

C5–C9 (terminal complement)

Answer

C1q

Answer

C3

Answer

C4b

Question 6

A 40-year-old presents with chronic diarrhea, weight loss, and CD4 count of 50 cells/µL. Stool acid-fast staining shows 4–6 µm oocysts. What is the causative organism?

Accepted Answer

Cryptosporidium parvum

Answer

Giardia lamblia

Answer

Isospora belli

Answer

Cyclospora cayetanensis

A 60-year-old renal transplant recipient presents with fever and a rising serum creatinine 3 months post-transplant.CMV antigenemia assay is positive.What is the treatment of choice?

A 60-year-old renal transplant recipient presents with fever and a rising serum creatinine 3 months post-transplant.
CMV antigenemia assay is positive.
What is the treatment of choice?