Regulations and Compliance Flashcards
7 cards from real ALAT practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 Regulations and Compliance flashcards as text
Under the Animal Welfare Act, which federal agency is responsible for inspecting research facilities that use regulated animals?
Answer: USDA APHIS
USDA APHIS (Animal and Plant Health Inspection Service) conducts unannounced inspections of AWA-regulated research facilities.
The 'three Rs' framework in animal research stands for which of the following?
Answer: Reduce, Refine, Replace
The three Rs—Replace, Reduce, and Refine—are guiding principles for minimizing animal use and suffering in research.
An IACUC must include which of the following members at minimum?
Answer: A veterinarian, a scientist, a non-scientist, and a non-affiliated member
Federal regulations require an IACUC to include at minimum a veterinarian, a practicing scientist, a non-scientist, and a member unaffiliated with the institution.
Which document must a research facility file with USDA APHIS annually under the Animal Welfare Act?
Answer: Annual Report of Research Facility
Registered research facilities must submit an Annual Report to USDA APHIS detailing animal usage and pain/distress classifications.
Pain and distress categories in USDA annual reports are classified using which system?
Answer: Columns B, C, D, and E
USDA annual reports use Columns B, C, D, and E to classify animals by the level of pain, distress, or use of pain-relieving drugs.
Which federal law specifically requires institutions receiving PHS funding to establish an animal care and use program consistent with the Guide for the Care and Use of Laboratory Animals?
Answer: Public Health Service Policy
The PHS Policy on Humane Care and Use of Laboratory Animals requires PHS-funded institutions to follow the Guide and maintain an Animal Welfare Assurance with NIH OLAW.
If an ALAT observes that a colleague is not following an approved IACUC protocol during a procedure, what is the most appropriate immediate action?
Answer: Report the deviation to the supervisor or veterinarian promptly
Protocol deviations must be reported promptly to a supervisor or veterinarian so corrective action and required IACUC reporting can occur.