ABP ABP Pharmacology and Antimicrobials

Question 1

Which systemic antibiotic combination is most commonly used as an adjunct to scaling and root planing for aggressive periodontitis?

Accepted Answer

Amoxicillin + metronidazole

Answer

Doxycycline + azithromycin

Answer

Ciprofloxacin + clindamycin

Answer

Penicillin + tetracycline

Question 2

What is the mechanism of action of subantimicrobial-dose doxycycline (SDD) when used as a periodontal adjunct?

Accepted Answer

Matrix metalloproteinase inhibition

Answer

Direct bactericidal activity

Answer

Disruption of bacterial cell membranes

Answer

Inhibition of protein synthesis in pathogens

Question 3

Which locally delivered antimicrobial agent releases doxycycline hyclate directly into the periodontal pocket?

Accepted Answer

Atridox (doxycycline hyclate 10%)

Answer

Arestin (minocycline microspheres)

Answer

PerioChip (chlorhexidine gluconate)

Answer

Elyzol (metronidazole gel)

Question 4

For a patient allergic to penicillin requiring prophylactic antibiotic coverage before periodontal surgery, which agent is the preferred alternative?

Accepted Answer

Clindamycin 600 mg

Answer

Metronidazole 500 mg

Answer

Azithromycin 500 mg

Answer

Doxycycline 100 mg

Question 5

Chlorhexidine gluconate oral rinse at 0.12% is considered most effective when used in which clinical scenario?

Accepted Answer

Post-surgical infection prevention and plaque suppression

Answer

Long-term plaque control replacement for brushing

Answer

Short-term adjunct during acute pericoronitis management

Answer

Daily rinse for all recall periodontal patients

Question 6

Which tetracycline has the highest affinity for binding to the root surface and is used in root biomodification protocols?

Accepted Answer

Tetracycline HCl

Answer

Doxycycline

Answer

Minocycline

Answer

Oxytetracycline