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AANPCB Diagnostic Testing and Interpretation Flashcards

6 cards from real AANPCB practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

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  1. A patient with suspected deep vein thrombosis has a low pre-test probability and a negative D-dimer. What is the most appropriate next step?

    Answer: DVT can be safely excluded without further testing

    In low pre-test probability patients, a negative D-dimer has a high negative predictive value and safely excludes DVT without the need for further imaging.

  2. Which interpretation of an ankle-brachial index (ABI) of 0.65 is correct?

    Answer: Moderate peripheral artery disease with claudication likely

    An ABI of 0.41–0.70 indicates moderate PAD, typically associated with intermittent claudication; values in this range warrant risk factor modification and possible vascular referral.

  3. A throat culture is positive for group A streptococcus (GAS) in a patient with pharyngitis. What is the primary reason to treat this infection?

    Answer: To prevent rheumatic fever and its cardiac sequelae

    The primary indication for treating GAS pharyngitis is prevention of acute rheumatic fever, which can cause permanent cardiac valve damage (rheumatic heart disease).

  4. Which value of estimated glomerular filtration rate (eGFR) defines Stage 3a chronic kidney disease per KDIGO guidelines?

    Answer: eGFR 45–59

    KDIGO classifies CKD Stage 3a as eGFR 45–59 mL/min/1.73m², representing mildly to moderately decreased kidney function that requires monitoring and risk factor control.

  5. A patient's INR is 3.8 while on warfarin therapy for atrial fibrillation; the goal is 2.0–3.0. The patient has no active bleeding. What is the most appropriate management?

    Answer: Hold warfarin dose and recheck INR in 1–2 days

    For a supratherapeutic INR of 3.1–5.0 without bleeding, holding warfarin temporarily and rechecking within 1–2 days is appropriate per ACCP guidelines before adjusting the maintenance dose.

  6. Which finding on a lipid panel represents the strongest independent risk factor for cardiovascular disease in primary prevention?

    Answer: LDL-C above 130 mg/dL

    Elevated LDL-C is the primary modifiable lipid target for cardiovascular risk reduction, and reducing LDL has the strongest evidence base for preventing atherosclerotic events.