AANP Pharmacology 3

Question 1

Which blood pressure medication class is absolutely contraindicated in pregnancy due to teratogenicity?

Accepted Answer

ACE inhibitors

Answer

Methyldopa

Answer

Labetalol

Answer

Nifedipine

Question 2

What is the first-line treatment for community-acquired pneumonia (CAP) in an otherwise healthy outpatient adult?

Accepted Answer

Azithromycin or doxycycline

Answer

Amoxicillin-clavulanate

Answer

Levofloxacin

Answer

Ceftriaxone

Question 3

A patient on warfarin is started on rifampin. How does this affect warfarin dosing?

Accepted Answer

Warfarin dose must be increased due to CYP induction

Answer

Warfarin dose must be decreased due to reduced metabolism

Answer

No dose change is needed

Answer

Warfarin should be permanently discontinued

Question 4

Which medication used for gout prevention requires monitoring for ocular toxicity, including retinal damage?

Accepted Answer

Hydroxychloroquine

Answer

Allopurinol

Answer

Probenecid

Answer

Colchicine

Question 5

Which drug interaction can occur when combining an MAOI with meperidine (pethidine)?

Accepted Answer

Serotonin syndrome, potentially fatal

Answer

Hypertensive crisis only

Answer

Anticholinergic toxicity

Answer

Neuroleptic malignant syndrome

Question 6

A patient asks about taking St. John's Wort for mild depression while on oral contraceptives. What is the key concern?

Accepted Answer

Reduced OCP efficacy leading to potential pregnancy

Answer

Increased sedation risk

Answer

Increased risk of serotonin syndrome

Answer

No clinical concern