PTCB Drug Test #3 3 — Questions and Answers
Question 1: Which of the following drugs is used to reverse opioid overdose?
- Flumazenil
- Naloxone (Correct answer)
- Naltrexone
- Buprenorphine
Correct answer: Naloxone
Naloxone (Narcan) is the opioid antagonist used for emergency reversal of opioid overdose. Flumazenil reverses benzodiazepines. Naltrexone prevents relapse. Buprenorphine is a partial agonist.
Question 2: A patient needs 2.5 g of a drug. The stock solution is 500 mg/mL. How many mL are required?
- 10 mL
- 2.5 mL
- 5 mL (Correct answer)
- 20 mL
Correct answer: 5 mL
2.5 g = 2500 mg. Volume = 2500 mg ÷ 500 mg/mL = 5 mL.
Question 3: What class of drug is duloxetine (Cymbalta)?
- SSRI
- TCA
- SNRI (Correct answer)
- MAO inhibitor
Correct answer: SNRI
Duloxetine (Cymbalta) is an SNRI (serotonin-norepinephrine reuptake inhibitor) used for depression, anxiety, diabetic neuropathy, and fibromyalgia.
Question 4: Which of the following requires refrigeration for storage?
- Metformin tablets
- Levothyroxine tablets
- Amoxicillin reconstituted suspension (Correct answer)
- Atorvastatin tablets
Correct answer: Amoxicillin reconstituted suspension
Amoxicillin suspension, once reconstituted, must be refrigerated (2–8°C) and discarded after 10–14 days. Tablets and capsules are generally stored at room temperature.
Question 5: Sildenafil (Viagra) belongs to which drug class?
- Alpha blocker
- PDE-5 inhibitor (Correct answer)
- Beta blocker
- Calcium channel blocker
Correct answer: PDE-5 inhibitor
Sildenafil is a phosphodiesterase-5 (PDE-5) inhibitor that increases cGMP, causing smooth muscle relaxation and vasodilation, used for erectile dysfunction and pulmonary arterial hypertension.
Question 6: Which antibiotic class should be avoided in patients with penicillin allergy due to cross-reactivity risk?
- Macrolides
- Fluoroquinolones
- Tetracyclines
- Cephalosporins (Correct answer)
Correct answer: Cephalosporins
Cephalosporins share a beta-lactam ring structure with penicillins, creating a potential for cross-reactivity (approximately 1–2%). Patients with severe penicillin allergy require caution.
PTCB Drug Test #3 3
Which of the following drugs is used to reverse opioid overdose?