PTCB Drug Test #3 2 — Questions and Answers
Question 1: Which of the following is NOT a common side effect of ACE inhibitors?
- Dry cough
- Hyperkalemia
- Bradycardia (Correct answer)
- Angioedema
Correct answer: Bradycardia
Bradycardia (slow heart rate) is NOT a typical ACE inhibitor side effect. Common side effects include dry cough (due to bradykinin accumulation), hyperkalemia, and rarely angioedema.
Question 2: A prescription reads: Prednisone 10 mg, take 4 tablets on day 1, 3 tablets on day 2, 2 tablets on day 3, 1 tablet on day 4. What is the total quantity to dispense?
- 8 tablets
- 12 tablets
- 10 tablets (Correct answer)
- 16 tablets
Correct answer: 10 tablets
4 + 3 + 2 + 1 = 10 tablets. This is a classic steroid taper (dose pack) regimen.
Question 3: What is the brand name for montelukast?
- Flovent
- Singulair (Correct answer)
- Advair
- Spiriva
Correct answer: Singulair
Singulair is the brand name for montelukast, a leukotriene receptor antagonist used for asthma prophylaxis and allergic rhinitis.
Question 4: Naproxen is classified as which type of drug?
- Opioid analgesic
- NSAID (Correct answer)
- Acetaminophen derivative
- Cox-2 inhibitor
Correct answer: NSAID
Naproxen (Aleve, Naprosyn) is a non-selective NSAID (nonsteroidal anti-inflammatory drug) that inhibits both COX-1 and COX-2 enzymes.
Question 5: Which of the following drugs requires a REMS (Risk Evaluation and Mitigation Strategy) program?
- Lisinopril
- Isotretinoin (Correct answer)
- Metoprolol
- Omeprazole
Correct answer: Isotretinoin
Isotretinoin (Accutane) requires the iPLEDGE REMS program due to severe teratogenicity. Prescribers, pharmacies, and patients must all be enrolled.
Question 6: Which drug interaction should be monitored when a patient takes warfarin with NSAIDs?
- Decreased warfarin efficacy
- Increased bleeding risk (Correct answer)
- Reduced NSAID absorption
- Enhanced NSAID metabolism
Correct answer: Increased bleeding risk
NSAIDs + warfarin significantly increases bleeding risk. NSAIDs inhibit platelet aggregation and can cause GI bleeding, while warfarin impairs coagulation. INR should be closely monitored.
PTCB Drug Test #3 2
Which of the following is NOT a common side effect of ACE inhibitors?