PTCB Drug Test #2 3 — Questions and Answers
Question 1: A physician orders vancomycin 1 g IV every 12 hours. Available: vancomycin 500 mg/vial. How many vials are needed per day?
- 2 vials
- 6 vials
- 4 vials (Correct answer)
- 3 vials
Correct answer: 4 vials
1 g = 1000 mg. Each dose requires 1000 mg ÷ 500 mg = 2 vials. With 2 doses per day: 2 x 2 = 4 vials per day.
Question 2: Which of the following SSRIs has the longest half-life, making it less likely to cause discontinuation syndrome?
- Paroxetine
- Sertraline
- Fluoxetine (Correct answer)
- Citalopram
Correct answer: Fluoxetine
Fluoxetine has the longest half-life (~1–6 days for parent drug, ~4–16 days for active metabolite norfluoxetine), making discontinuation syndrome much less common than with other SSRIs.
Question 3: Which of the following is the brand name for lisdexamfetamine?
- Adderall
- Ritalin
- Concerta
- Vyvanse (Correct answer)
Correct answer: Vyvanse
Vyvanse is the brand name for lisdexamfetamine dimesylate, a prodrug Schedule II stimulant used for ADHD and binge eating disorder.
Question 4: What is the mechanism of action of ACE inhibitors?
- Block aldosterone receptors
- Prevent conversion of angiotensin I to angiotensin II (Correct answer)
- Block angiotensin II receptors
- Inhibit renin directly
Correct answer: Prevent conversion of angiotensin I to angiotensin II
ACE inhibitors block the angiotensin-converting enzyme, preventing the conversion of angiotensin I to angiotensin II, which lowers blood pressure and reduces aldosterone secretion.
Question 5: Which of the following is classified as a Schedule IV controlled substance?
- Alprazolam (Correct answer)
- Buprenorphine
- Morphine
- Methylphenidate
Correct answer: Alprazolam
Alprazolam (Xanax) is a Schedule IV benzodiazepine. Buprenorphine is Schedule III, morphine is Schedule II, and methylphenidate is Schedule II.
Question 6: Rosuvastatin is marketed under which brand name?
- Lipitor
- Zocor
- Crestor (Correct answer)
- Pravachol
Correct answer: Crestor
Crestor is the brand name for rosuvastatin, a high-intensity statin that provides significant LDL reduction with a relatively low dose.
PTCB Drug Test #2 3
A physician orders vancomycin 1 g IV every 12 hours.
Available: vancomycin 500 mg/vial.
How many vials are needed per day?