CET CET Medication Safety & Pharmacology 1 — Questions and Answers
Question 1: Which medication is most commonly used for conscious sedation during endoscopy procedures?
- Midazolam (Correct answer)
- Metformin
- Metoprolol
- Metronidazole
Correct answer: Midazolam
Midazolam is a benzodiazepine used for conscious sedation during endoscopy due to its anxiolytic and amnestic properties.
Question 2: What is the reversal agent for benzodiazepines administered during endoscopy sedation?
- Naloxone
- Flumazenil (Correct answer)
- Atropine
- Epinephrine
Correct answer: Flumazenil
Flumazenil competitively antagonizes benzodiazepine receptors and is the specific reversal agent for midazolam-related over-sedation.
Question 3: Which short-acting opioid is most frequently combined with midazolam for endoscopy sedation?
- Morphine
- Codeine
- Fentanyl (Correct answer)
- Oxycodone
Correct answer: Fentanyl
Fentanyl's rapid onset and short duration make it the preferred opioid analgesic paired with midazolam in endoscopy suites.
Question 4: What is the reversal agent for opioid-induced respiratory depression during endoscopy?
- Flumazenil
- Naloxone (Correct answer)
- Neostigmine
- Protamine
Correct answer: Naloxone
Naloxone (Narcan) is the mu-opioid receptor antagonist used to reverse opioid-induced respiratory depression during endoscopy.
Question 5: Which topical anesthetic is commonly applied to the posterior pharynx before upper endoscopy to suppress the gag reflex?
- Lidocaine (Correct answer)
- Bupivacaine
- Ropivacaine
- Procaine
Correct answer: Lidocaine
Lidocaine spray or viscous solution is applied to the posterior pharynx before upper endoscopy to reduce the gag reflex and patient discomfort.
Question 6: Propofol used for deep sedation in endoscopy must be administered by whom?
- The endoscopy technician
- A trained anesthesia provider (Correct answer)
- Any registered nurse
- The gastroenterologist only
Correct answer: A trained anesthesia provider
Propofol's narrow therapeutic window and risk of rapid respiratory depression require it to be administered by a qualified anesthesia provider such as an anesthesiologist or CRNA.
CET CET Medication Safety & Pharmacology 1
Which medication is most commonly used for conscious sedation during endoscopy procedures?