ACBN Practice Questions 3 — Questions and Answers
Question 1: Which lipoprotein is primarily responsible for transporting cholesterol from the liver to peripheral tissues?
- HDL
- LDL (Correct answer)
- VLDL
- Chylomicrons
Correct answer: LDL
LDL (low-density lipoprotein) transports cholesterol from the liver to peripheral tissues and is the primary carrier of cholesterol in circulation.
Question 2: A patient with chronic kidney disease stage 4 should typically restrict which nutrient to slow disease progression?
- Carbohydrate
- Protein (Correct answer)
- Unsaturated fat
- Soluble fiber
Correct answer: Protein
Protein restriction in CKD stage 4 reduces the nitrogen load on failing kidneys and can slow the rate of GFR decline.
Question 3: The body mass index (BMI) threshold for obesity classification in adults according to standard clinical guidelines is:
- BMI ≥ 25 kg/m²
- BMI ≥ 27 kg/m²
- BMI ≥ 30 kg/m² (Correct answer)
- BMI ≥ 35 kg/m²
Correct answer: BMI ≥ 30 kg/m²
A BMI of 30 kg/m² or greater is classified as obesity (Class I), while 25-29.9 is overweight, according to WHO and CDC guidelines.
Question 4: Which vitamin functions as a coenzyme in over 100 enzymatic reactions and is crucial for amino acid metabolism and neurotransmitter synthesis?
- Vitamin B1 (Thiamine)
- Vitamin B2 (Riboflavin)
- Vitamin B6 (Pyridoxine) (Correct answer)
- Vitamin B12 (Cobalamin)
Correct answer: Vitamin B6 (Pyridoxine)
Vitamin B6 (pyridoxine), as pyridoxal phosphate (PLP), is a coenzyme in over 100 enzymatic reactions, particularly transamination and decarboxylation in amino acid metabolism.
Question 5: The Mifflin-St Jeor equation is primarily used to estimate which component of energy expenditure?
- Thermic effect of food
- Physical activity level
- Resting metabolic rate (RMR) (Correct answer)
- Total daily energy expenditure
Correct answer: Resting metabolic rate (RMR)
The Mifflin-St Jeor equation estimates resting metabolic rate using body weight, height, age, and sex, and is considered one of the most accurate predictive equations for RMR.
Question 6: In the context of enteral nutrition, a gastric residual volume (GRV) above what threshold typically prompts clinical reassessment for aspiration risk?
- 50 mL
- 100 mL
- 200-250 mL (Correct answer)
- 500 mL
Correct answer: 200-250 mL
A gastric residual volume above 200-250 mL is generally the clinical threshold that prompts reassessment of enteral feeding tolerance and aspiration risk.
Question 7: Which sugar alcohol is most commonly associated with a significant laxative effect due to its incomplete absorption in the small intestine?
- Erythritol
- Sorbitol (Correct answer)
- Xylitol
- Mannitol
Correct answer: Sorbitol
Sorbitol is poorly absorbed in the small intestine and is fermented by colonic bacteria, causing osmotic diarrhea and bloating at moderate to high intakes.
Which lipoprotein is primarily responsible for transporting cholesterol from the liver to peripheral tissues?